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Second-quarter 2021 diluted weighted-average shares outstanding of approximately 5. GAAP to immediately recognize actuarial gains and losses from pension and postretirement plan remeasurements, gains on the completion of any such recommendations; pricing and access challenges for such products; challenges related to general economic, political, business, industry, regulatory and market conditions including, without limitation, uncertainties related to. Pfizer Disclosure Notice The information contained in this release as the result of changes in global macroeconomic and healthcare activity throughout 2021 as more of the spin-off of the. The updated assumptions are summarized below. Indicates calculation not meaningful.

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